The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology symptoms erythematosus immunology lupus orthopedics sle achilles anaphylaxis femoralhead fractures gastrointestinal hypersensitivityreaction musculoskeletal ra rheumatoidarthritis takayasus tendonrupture type1
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... Patient's immune system ... cells recruited Complications ... : • Acute Asthma
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... Vasculitis -> Acute ... distension #Systemic ... Gastrointestinal #Complications ... pathophysiology #signs
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to a likely allergen ... exposure to known allergen ... symptoms in the acute ... / Symptoms / Complications
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... weight-bear • Arthritic ... FemoralHead #Fractures #msk ... pathophysiology #signs
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis #signs ... pathophysiology #msk
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... • Non-specific Acute-phase ... deviation, etc • Systemic ... Extra-articular signs ... pathophysiology #signs
Takayasu’s Arteritis: Pathogenesis and clinical findings - Fatigue, weight loss, low grade fever, arthralgias - Incr
Takayasu’s Arteritis ... , Incr risk of Acute ... Syndrome - >10mmHg systolic ... #Takayasus #Arteritis ... Vasculitis #Diagnosis #Signs
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