The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis symptoms caudaequina erythematosus femoralhead gait genetics henochscholeinpurpura hsp iga lupus musculoskeletal orthopedics pagetsdisease pediatrics praderwilli sle systemic trendelenburg vasculitis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
/Symptoms/Complications ... weight-bear • Arthritic ... #msk #diagnosis ... #pathophysiology ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms ... /Complications: ... Incr Skeletal fractures ... #genetics #pathophysiology ... #peds #pediatrics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... #pathophysiology ... #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... lumbar spine Signs ... / Symptoms / Complications ... #MSK #pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
of the Hip • Arthritis ... Greater Trochanter Fracture ... #causes #symptoms ... #signs #diagnosis ... #msk
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
necrosis factor a inhibitors ... nephrotic/nephritic syndrome ... Arthralgia's (common), arthritis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... PagetsDisease #pathophysiology ... #diagnosis #signs
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