The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
experienced BPD Mnemonic ... BPD #Borderline #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... GravesDisease #pathophysiology ... endocrinology #symptoms #signs ... #diagnosis
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
familiarity SPD Mnemonic ... #Schizotypal #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
themselves DPD Mnemonic ... DPD #Dependent #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... erythematosus (SLE) Signs ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Cardiovascular disease ... Overproduction #diagnosis ... #signs #symptoms ... endocrinology #pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... #signs #psychiatry