The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis symptoms lupus sle erythematosus systemic acute alcohol alcoholusedisorder anaphylaxis ankylosingspondylitis benzodiazepine bzd chronic closedangle extraarticular gastrointestinal glaucoma hypertensive keratoconus
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
to effects of EtOH ... exacerbated by EtOH ... • Withdrawal ... #Pathophysiology ... #Diagnosis #Signs
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... / Symptoms / Complications ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... Mucocutaneous #Manifestations ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Clinical Findings and Complications ... Note: Opioid withdrawal ... #Opiate #Pathophysiology ... #Diagnosis #Signs
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Pathogenesis and Ocular Manifestations ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
> Keratoconus Signs ... / Symptoms / Complications ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Alcohol Withdrawal: Clinical Findings and Complications The onset of alcohol withdrawal generally begins 6-24 hours after the
Clinical Findings and Complications ... >2 days after EtOH ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #EtOH
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