The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
#OtitisMedia #pathophysiology ... #diagnosis #symptoms ... #signs #peds #pediatrics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds ... #pediatrics
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
- Must have >3 symptoms ... >18 years old, criteria ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
AnorexiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry ... #RiskFactors
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
- Must have >4 symptoms ... a sibling - Symptoms ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Toxicity Criteria ... Serotonin #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
BulimiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry ... #RiskFactors