The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis growthhormone pituitary 21hydroxylasedeficiency 21ohd affectivedisorder bipolar depression disorder excess feedbackloop genetics glftap macroadenoma majordepressivedisorder masseffects mdd mnemonic overproduction peds
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... MajorDepressiveDisorder #Depression #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
Bipolar #Disorder #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Seasonal Affective Disorder: Pathogenesis and clinical findings Symptoms (included in the DSM-V) - Two Major Depressive episodes
clinical findings Symptoms ... AffectiveDisorder #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
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