The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Reuptake Inhibitors: Mechanisms ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Inhibitors(SNRIs): Mechanisms ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Antipsychotics: Mechanisms ... Cardio-metabolic effects - Mechanism ... SecondGeneration #Mechanisms ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Antipsychotics: Mechanisms ... ThirdGeneration #Mechanisms ... #SideEffects #pharmacology ... #diagnosis #psychiatry
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Anti-Psychotics: Mechanisms ... Extrapyramidal Symptoms ... FirstGeneration #Mechanisms ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... / Complications ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
resolve by 72 hours Complications ... slide for full mechanisms ... pathophysiology #diagnosis ... #symptoms #signs
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation (complex mechanism ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
clinical findings and complications ... BZD #withdrawal #pharmacology ... pathophysiology #diagnosis ... #signs #symptoms