The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... palpation - Vasculitic ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings

#CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Complications Signs/Symptoms ... Stroke or TIA-like symptoms ... Complications #Signs #Symptoms ... #diagnosis #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... pathophysiology #signs #symptoms ... #diagnosis
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... have either 26 symptoms ... to 25 for new diagnosis ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... Pathophysiology #diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Leukocytoclastic vasculitis ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
trigger Physical Symptoms ... Psychological Symptoms ... PanicDisorder #Anxiety #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs