The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
paresthetica • Symptoms ... 3-6 months of symptom ... sensory nerve, thus symptoms ... mass Sensory Symptoms ... MeralgiaParesthetica #MSK
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
#SideEffects #Psychiatry ... Diagnosis #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
#SideEffects #Psychiatry ... Diagnosis #Signs #Symptoms
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
Pathogenesis and Symptoms ... cause the Positive Symptoms ... cause Negative Symptoms ... pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
cord - Signs and Symptoms ... diagnosis #signs #symptoms ... #msk
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... suicide Other Symptoms ... Pathophysiology #Signs #Symptoms ... #Psychiatry
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
with possible symptoms ... diagnosis #signs #symptoms ... #msk
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
StressFractures #msk ... pathophysiology #symptoms
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
• Withdrawal symptoms ... Diagnosis #Signs #Symptoms ... #Psychiatry