The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... the above with symptoms ... BPD #Borderline #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #signs #psychiatry ... #criteria
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
#Schizotypal #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
DPD #Dependent #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
AVPD #Avoidant #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
ASPD #Antisocial #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings
 • Arrogant, Haughty Behaviors or Attitude - Often display
#Narcissistic #PersonalityDisorder ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
- Must have >3 symptoms ... >18 years old, criteria ... #Conduct #CD #BehavioralDisorder ... #signs #psychiatry ... #criteria