The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology criteria behavioraldisorder mooddisorders obsessivecompulsive ocpd riskfactors alcoholusedisorder amsuicide anorexianervosa antisocial aseptic aspd avoidant avpd bipolar borderline bpd bulimianervosa
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings Psychological Hypothesis • Cognitive behavioral model: Emotional disturbance arising from
maladaptive beliefs and anxiety ... Dysregulation of anxiety ... ObsessiveCompulsive #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Signs #Symptoms
Borderline Personality Disorder: Pathogenesis and Clinical Findings Behavioral Traits: • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... BPD #Borderline #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... A good mnemonic ... Signs / Symptoms ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings Cognitive-Perceptual • Magical thinking - Belief in paranormal or
reference - Anxiety ... #Schizotypal #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
startle reflex • Anxiety ... Pathophysiology #diagnosis #symptoms ... #signs #psychiatry
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
and hypothalamic-pituitary-adrenal ... carrying anti-anxiety ... Anticipatory Anxiety ... PanicDisorder #Anxiety ... #signs #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... suicide Other Symptoms ... partum onset) - Anxiety ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
• Withdrawal symptoms ... , seizure, and anxiety ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Psychiatry
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