The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
maladaptive beliefs and anxiety ... Dysregulation of anxiety ... ObsessiveCompulsive #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Signs #Symptoms
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... BPD #Borderline #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... A good mnemonic ... Signs / Symptoms ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
reference - Anxiety ... #Schizotypal #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... partum onset) - Anxiety ... MoodDisorders #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
and hypothalamic-pituitary-adrenal ... carrying anti-anxiety ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
• Withdrawal symptoms ... , seizure, and anxiety ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Psychiatry
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
themselves DPD Mnemonic ... DPD #Dependent #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
- Incr guilt, anxiety ... MoodDisorders #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Psychiatry