The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
acetabular wall • Anterior ... femoral head onto anterior ... onto lateral hip Signs ... /Symptoms/Complications ... #msk #diagnosis
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Trendelenburg Gait ... Greater Trochanter Fracture ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Dysfunction, Weight gain ... Incr NE: Nausea ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
sensory • Before diagnosis ... abnormalities (gait ... ligament (near anterior ... MeralgiaParesthetica #MSK ... #signs #symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Anterior Shoulder ... glenoid -> Acute ... #Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... rupture - Antalgic gait ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Cord Syndrome -> Anterior ... Injury #Syndromes #diagnosis ... pathophysiology #signs ... #symptoms #msk
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Acne • Coarse features ... tolerance • Weight gain ... Overproduction #diagnosis ... #signs #symptoms
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
brain • Weight Gain ... Extrapyramidal Symptoms ... , and/or limbs caused ... bradykinesia/akinesia • Acute ... #pharmacology #diagnosis
Chronic Exertional Compartment Syndrome (CECS)
 • Diagnosis Of CECS requires patient to undergo the same exertional
activity that causes ... • Diagnostic ... criteria for CECS ... #signs #symptoms ... #msk