The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs pathophysiology arteritis extraarticular lupus ra rheumatoidarthritis sle achilles ankylosingspondylitis erythematosus gastrointestinal giantcell msk mucocutaneous opiate opioid orthopedics otitismedia
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... -> Acute Pancreatitis ... Gastrointestinal #Complications ... pathophysiology #signs #symptoms
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Clinical findings and Complications ... Signs/Symptoms ... Temporal #Arteritis #Complications ... #Signs #Symptoms ... #diagnosis #Vasculitis
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Polyarteritis Nodosa (PAN ... swelling - GI Manifestations ... multiplex #PAN ... Diagnosis #Signs #Symptoms ... #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... Livedo Reticularis, Vasculitis ... Mucocutaneous #Manifestations ... diagnosis #signs #symptoms ... #complications
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Acute Otitis Media ... severe Signs/Symptoms ... • Otalgia (Ear Pain ... Balance Problems #Acute ... pathophysiology #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... /Complications: ... squeeze test) - Pain ... diagnosis #signs #symptoms
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... Opioid withdrawal can ... Symptoms can take ... are more acute ... The less acute behavioral
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... -> Sudden eye pain ... pleuritic chest pain ... pathophysiology #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
poly-articular joint pain ... Extra-articular manifestations ... • Non-specific Acute-phase ... arthralgia (joint pain ... pathophysiology #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... visual acuity, eye pain ... - Inflammation acute ... #Complications ... diagnosis #signs #symptoms
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