The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification of ... and Complications ... #Classification ... #Orthopedics #MSK ... #diagnosis #complications
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open Fractures: ... and Complications ... Gustilo-Anderson Classification ... #Diagnosis #Complications ... #MSK #Orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... #PraderWilli #Syndrome
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Signs/Symptoms/Complications ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... - Budd Chiari Syndrome ... Gastrointestinal #Complications ... signs #symptoms #diagnosis
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
reaction, Myasthenia Gravis ... , Graves' Disease ... Stevens-Johnson Syndrome ... Reactions #Types #Classification ... #Diagnosis #Definitions
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Signs / Symptoms / Complications ... #CaudaEquina #Syndrome ... #MSK #pathophysiology ... #diagnosis #symptoms
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
weight loss, low grade ... Acute Coronary Syndrome ... Takayasus #Arteritis #Vasculitis ... #Diagnosis #Signs
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Anorexia Nervosa: Complications ... increased risk of fracture ... Death - Cardiac complications ... highest mortality rates ... pathophysiology #diagnosis
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... pathophysiology #diagnosis ... signs #symptoms #complications