The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... : Mechanisms and ... • Serotonin Syndrome ... #Pathophysiology ... #Pharmacology #
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
Benzodiazepines: ... Mechanism of Action ... Depression #Benzodiazepines ... #Psychiatry #Pharmacology ... #pathophysiology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... (SNRIs): Mechanisms ... Vomiting Serotonin Syndrome ... #Pathophysiology ... #Pharmacology #
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Mood Stabilizers: Mechanism ... Allergic reaction -> Benign ... Stevens-Johnson Syndrome ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... Syndrome • Crush ... local signalling mechanisms ... compartment pressure #Acute ... CompartmentSyndrome #ACS #pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... outflow - PDE-5 inhibitors ... inflammation #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Benzodiazepine ( ... Asthma. or sense of being ... sudden death #Benzodiazepine ... BZD #withdrawal #pharmacology ... #pathophysiology
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
life-threatening (exceptions being ... alcohol and/or benzodiazepines ... symptoms are more acute ... The less acute behavioral ... Withdrawal #Opiate #Pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
continue growing (mechanism ... estrogen secretion -> inhibits ... growth (this is one mechanism ... Polycystic Ovarian Syndrome ... #OvarianCycle #pathophysiology