The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... - Budd Chiari Syndrome ... Gastrointestinal #Complications ... #pathophysiology
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Gout: Pathogenesis ... Medications (ASA, ACE ... Hyperuricemia #Pathophysiology ... #Complications ... #Gout #Tophaceous
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Pathogenesis and Complications ... renal tubules - ACE-inhibitors ... Hyperuricemia #Pathophysiology ... #Complications ... #Gout
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... Syndrome • Crush ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... must be ruled out ... bodies, shallow ACD ... Signs / Symptoms / Complications ... ClosedAngle #Glaucoma #pathophysiology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... throughout body (mouth, gut ... bradykinesia/akinesia • Acute ... #SideEffects #pharmacology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
recognizes allergen as ... Allergen-specific lgE Abs ... cells recruited Complications ... : • Acute Asthma ... Allergy #Immunology #pathophysiology
Isolated Anterior Cruciate Ligament (ACL) Injury: Pathogenesis and clinical findings
 • Feeling a "pop"
 • Acute
Cruciate Ligament (ACL ... Feeling a "pop" • Acute ... knee is "giving out ... AnteriorCruciateLigament #ACL ... #MSK #Sports #pathophysiology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
clinical findings and complications ... Activation of ACC ... BZD #withdrawal #pharmacology ... #pathophysiology