The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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symptoms erythematosus orthopedics sle systemic achilles alzheimersdisease ankylosingspondylitis avascularnecrosis caudaequina dementia extraarticular gastrointestinal geriatrics injury manifestations musculoskeletal neurology pagetsdisease primary
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... - Budd Chiari Syndrome ... #pathophysiology ... #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms ... #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... RA) or systemic lupus ... #Pathophysiology ... #Diagnosis #Signs
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... /Symptoms/Complications ... TendonRupture #diagnosis ... #pathophysiology ... #msk #orthopedics
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... / Symptoms / Complications ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... / Symptoms / Complications ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
- Sickle-cell disease ... therapy - Lupus ... affected) - Acute ... AvascularNecrosis #pathophysiology ... #diagnosis #signs
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Complications ... bone formation MSK ... PagetsDisease #pathophysiology ... #diagnosis #signs
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Inflammatory Bowel Disease ... - Inflammation acute ... Manifestations #Complications ... #pathophysiology ... #diagnosis #signs
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