The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(RA) or systemic ... erythematosus (SLE ... ) Signs / Symptoms ... #Pathophysiology ... #Diagnosis #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... • Serotonin Syndrome ... #Pathophysiology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... Vomiting Serotonin Syndrome ... #Pathophysiology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus (SLE ... - Arthralgia, Arthritis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Erythematosus #SLE ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
Psoriatic Arthritis ... polyarthritis (like RA ... PsoriaticArthritis #pathophysiology ... #diagnosis #signs ... #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... (RA): Extra-articular ... #pathophysiology ... #signs #symptoms ... #diagnosis #ExtraArticular
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... : - Coronary Arteritis ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... Extra-articular signs ... #pathophysiology ... #signs #symptoms ... #diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
necrosis factor a inhibitors ... nephrotic/nephritic syndrome ... Arthralgia's (common), arthritis ... #Diagnosis #Signs ... #Symptoms