The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology complications lupus sle erythematosus extraarticular ra rheumatoidarthritis systemic acute adhesivecapsulitis ankylosingspondylitis bakerscyst cranialarteritis criteria differential frozenshoulder gastrointestinal giantcellarteritis injury
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
sensory • Before diagnosis ... intervertebral disc disease ... MeralgiaParesthetica #MSK ... #differential #diagnosis ... #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... interstitial lung disease ... pathophysiology #signs ... #symptoms #diagnosis
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
swelling - GI Manifestations ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... Livedo Reticularis, Vasculitis ... Mucocutaneous #Manifestations ... pathophysiology #diagnosis ... #signs #symptoms
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... hands & feet Signs ... /Symptoms/Complications ... #Symptoms #Vasculitis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... Extra-articular manifestations ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Injury #Syndromes #diagnosis ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees) • Incr Axial rotation of thoracic
Restrictive Pulmonary Disease ... pathophysiology #msk ... #diagnosis #signs ... #symptoms
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