The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs symptoms complications sle erythematosus rheumatoidarthritis acute comparison degenerative diffuse extraarticular gastrointestinal inflammatory injury jointdisease jointpain manifestations mucocutaneous musculoskeletal neurology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Lupus #Erythematosus ... Complications #pathophysiology ... signs #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology ... signs #symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... rheumatoid arthritis (RA ... ) or systemic lupus ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis (RA ... blood vessels (vasculitis ... effusion on CXR • RA ... #pathophysiology ... signs #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis (RA ... diseases features • RA ... deviation, etc • Systemic ... #pathophysiology ... signs #symptoms #diagnosis
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
is oftentimes systemic ... Rheumatoid arthritis, Lupus ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Injury #Syndromes #diagnosis ... #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Diffuse Systemic ... Renal Failure - Mask ... #Scleroderma #pathophysiology ... signs #symptoms #diagnosis
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