The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology signs orthopedics fractures acute classification 21hydroxylasedeficiency achilles adhesivecapsulitis benign bph caudaequina differential endocrinology erythematosus femoralhead frozenshoulder genetics grades grading
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... #Syndromes #diagnosis ... pathophysiology #signs #symptoms ... #msk #orthopedics ... #neurology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... /Complications: ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
Myelopathy - Injury ... cord - Signs and Symptoms ... #Myelopathy #diagnosis ... #signs #symptoms ... #msk
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
Clinical Features and Complications ... Typically "inside out" injury ... Open #Fractures #Diagnosis ... #Complications ... #MSK #Orthopedics
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
Findings Compression/injury ... paresthetica • Symptoms ... sensory • Before diagnosis ... MeralgiaParesthetica #MSK ... #differential #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
cells -> Tissue injury ... Pancarditis and valvular injury ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
etiology Signs/Symptoms ... /Complications: ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... possible vascular injury ... - Type 1 or 2 injury ... #Orthopedics #MSK ... #diagnosis #complications
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