The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs msk acute orthopedics 21hydroxylasedeficiency 21ohd adhesivecapsulitis affectivedisorder benign bph complications differential dysfunction endocin erectile excess femoralhead fractures frozenshoulder
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... #Syndromes #diagnosis ... pathophysiology #signs #symptoms ... #orthopedics #neurology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Thyroid gland hyperplasia ... etiology Signs/Symptoms ... pathophysiology #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Benign Prostatic Hyperplasia ... Inflammation: Incr tissue injury ... chronic renal injury ... Pathophysiology #Urology ... #Diagnosis
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
Findings Compression/injury ... paresthetica • Symptoms ... 3-6 months of symptom ... sensory • Before diagnosis ... #differential #diagnosis
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
Myelopathy - Injury ... cord - Signs and Symptoms ... #Myelopathy #diagnosis ... #signs #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
cells -> Tissue injury ... Pancarditis and valvular injury ... pathophysiology #diagnosis ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... lateral hip Signs/Symptoms ... Fractures #msk #diagnosis ... pathophysiology #signs #symptoms
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
causes direct injury ... Pathophysiology #Diagnosis ... #Signs #Symptoms
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