The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
cells -> Tissue injury ... Pancarditis and valvular injury ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms ... #complications
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... /Complications: ... • Gonadal hypoplasia ... Syndrome #genetics #pathophysiology
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Complications of ... infections #Measles #Complications ... diagnosis #signs #symptoms ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... lateral hip Signs/Symptoms ... /Complications: ... msk #diagnosis #pathophysiology ... #signs #symptoms
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Thyroid gland hyperplasia ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... endocrinology #symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... Rapid onset of symptoms ... Signs / Symptoms ... / Complications ... #Anaphylaxis #pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic Hyperplasia ... Inflammation: Incr tissue injury ... chronic renal injury ... #Prostate #Pathophysiology ... #Urology #Signs
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Findings Compression/injury ... paresthetica • Symptoms ... 3-6 months of symptom ... mass Sensory Symptoms ... MeralgiaParesthetica #MSK #pathophysiology