The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis msk acute erythematosus genetics lupus pediatrics peds sle 21hydroxylasedeficiency 21ohd achilles benign bph endocrinology femoralhead fractures gastrointestinal incontinence mixed
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
tumour causing injury ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... distension #Systemic ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Avulsion or shearing injury ... /Symptoms/Complications ... msk #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteoporosis #Systemic ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
cells -> Tissue injury ... Pancarditis and valvular injury ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology ... #msk #orthopedics
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... : • Gonadal hypoplasia ... Syndrome #genetics #pathophysiology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Benign Prostatic Hyperplasia ... Inflammation: Incr tissue injury ... chronic renal injury ... #Prostate #Pathophysiology ... #Urology #Signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
usual defense system ... lower tract: As a complication ... UrinaryTractInfection #UUTI #Pathophysiology ... #Signs #Symptoms
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