The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
: Gastrointestinal ... the pancreas, Vasculitis ... #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Clinical findings and Complications ... Signs/Symptoms ... Hemorrhages #GiantCell ... Temporal #Arteritis #Complications ... #diagnosis #Vasculitis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... neurological findings #GiantCell ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... (100%) - Gastrointestinal ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... Symptoms can take ... myalgias) - Gastrointestinal ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Clinical Findings Diagnostic ... feet Signs/Symptoms ... /Complications: ... Disease #Criteria #Diagnosis ... #Vasculitis
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
cardiac muscle mass GASTROINTESTINAL ... mortality rates of all psychiatric ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... related to complications ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry