The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis complications sle erythematosus ra rheumatoidarthritis systemic arteritis avascularnecrosis dermatomyositis dm extraarticular henochscholeinpurpura iga msk mucocutaneous musculoskeletal pan pm polyarteritisnodosa
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
: Gastrointestinal ... Manifestations ... the pancreas, Vasculitis ... Complications #pathophysiology ... #signs #symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... neurological findings #GiantCell ... Temporal #Arteritis #Pathophysiology ... #Symptoms #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Musculoskeletal Manifestations ... Osteonecrosis Esp ... Complications #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Manifestations ... Livedo Reticularis, Vasculitis ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
(100%) - Gastrointestinal ... and ankles) #HSP ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... blood to limbs (esp ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
swelling - GI Manifestations ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
primarily deltoids and hip ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Vasculitis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Extra-articular manifestations ... boggy" joints, esp ... Extra-articular signs ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
therapy - Lupus ... hypolucency "Crescent sign ... AvascularNecrosis #pathophysiology ... #diagnosis #signs ... #symptoms
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