Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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diagnosis management hematology differential causes neurology acute aids anemia aplastic arterial associated cauda caudaequina coagulation common cvid dementia dic disorder
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Campylobacter jejuni - HIV ... Treatment: • Plasmapheresis ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- HIV • Immune ... immunodeficiency virus (HIV ... CMV) • Epstein-Barr ... aplastic anemia Treatment ... Anemia #oncology #hematology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... DDX: • Epstein-Barr ... antibody test) Treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Infection (Viral- HIV ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV ... dementia Pathophysiology ... The clinical syndrome ... Treatment: • HAART ... treatment • Cognitive
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Cauda Equina Syndrome ... Cauda Equina Syndrome ... cord infarct • HIV ... cord • Guillain-Barre ... axial T1 and T2 Treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Management: • Lifelong IV ... : • Nephrotic syndrome ... infections (Epstein-Barr ... syndrome, HIV) ... hypogammaglobulinemia #immunology #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... of HIV/AIDS patients ... a decrease in HIV ... albicans • Epstein Barr ... #Inflammatory #Syndrome
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hematological: - HIT ... • Nephrotic Syndrome ... Venous #Arterial #pathophysiology ... #hematology #differential
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