Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - HIV • Immune ... immunodeficiency virus (HIV ... Treatment: ... #oncology #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... - Hemolytic anemia ... • HCV, HBV Not ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Tamponade Pulmonary Causes ... syndrome Other Causes ... Transverse myelitis • Hematology ... : - Anemia
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Leukocytosis, anemia ... hemorrhage • Treatment ... #differential #causes
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
symptoms • >50,000 HIV ... elevation • Nausea ... 14%), in which case ... enzymes ↑ • Mild anemia ... antibody test) Treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... Treat primary cause ... #treatment #management ... #hematology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Infection (Viral- HIV ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... Management #Summary #causes ... #treatment
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... neoplasms - PNH - HIT ... Diagnosis #clots #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV ... dementia Pathophysiology ... : HIV frequently ... Treatment: • HAART ... treatment • Cognitive