Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
• Infectious: HAV ... , HCV, HEV, EBV, ... HSV, CMV • Neoplasm ... Differential #Diagnosis #causes ... #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... • HCV, HBV Not ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... APLS:PLT ↓ HEMATOLOGIC ... neoplasms - PNH - HIT ... Diagnosis #clots #hematology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Tamponade Pulmonary Causes ... syndrome Other Causes ... Transverse myelitis • Hematology ... differential #diagnosis #causes
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g., HIV ... - Infections (HIV ... Lymphomas • Other hematologic ... Tuberculosis • HIV ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... Treat primary cause ... #treatment #management ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hematological: - HIT ... considered in all cases ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - HIV • Immune ... immunodeficiency virus (HIV ... aplastic anemia Treatment ... Anemia #oncology #hematology
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
Causes of Pseudocellulitis ... Inflammatory Causes ... Neoplastic Causes ... Compartment syndrome • IV ... #dermatology #skin
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Infection (Viral- HIV ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... Management #Summary #causes ... #treatment