Acute Coronary Syndrome (ACS) Definitions - Stable Angina, Unstable Angina, NSTEMI, STEMI 1 STABLE ANGINA - Angina pain develops when there is increased demand in the setting of a stable atherosclerotic plaque. The vessel is unable to dilate enough to allow adequate blood flow to meet the myocardial 2 UNSTABLE ANGINA - The plaque ruptures and a thrombus forms around the ruptured plaque, causing partial occlusion of the vessel. Angina pain occurs at rest or progresses rapidly over a short period of time. 3 NSTEMI - During an NSTEMI, the plaque rupture and thrombus formation causes partial occlusion to the vessel that results in injury and infarct to the subendocardial myocardium. 4 STEMI - A STEMI is characterized by complete occlusion the blood vessel lumen, resulting in transmural injury and infarct to the myocardium, which is reflected by ECG changes and a rise in troponins. #Diagnosis #Cardiology #ACS #Unstable #Angina #NSTEMI #Definitions ** GrepMed Recommended Text: The Only EKG Book You'll Ever Need - https://amzn.to/2Z0uM1Y

Muscarinic Receptor Agonists and Antagonists Muscarinic Receptor Agonists Methacholine • Diagnosis of bronchial airway Carbachol • Glaucorna (topical administration) Bethanechol • Ileus (postoperative, neurogenic) • Urinary retention Pilocarpine • Glaucorna (topical administration) • Xerostomia due to Sjögren syndrome, Head and neck irradiation Cevimeline • Xerostomia due to Sjögren syndrome Muscarinic Receptor Antagonists Atropine • Acute symptomatic bradycardia (e.g., AV block) • Cholinesterase inhibitor intoxication • Aspiration prophylaxis Scopolamine • Motion sickness Homatropine, cyclopentolate, tropicamide • Ophthalmological examination (cycloplegia and mydriasis induction) Ipratropium, tiotropium, aclidinium. umeclidinium • COPD • Rhinorrhea (ipratropium) Pirenzepine, telenzepine • Peptic ulcer disease (notin US.) Oxybutynin, trospium, darifenacin, solifenacin, tolterodine, fesoterodine • Overactive bladder, enuresis, neurogenic bladder Glycopyrrolate • Duodenal ulcer • Sialorrhea Dicyclomine, hyoscyamine • Diarrhea-predominant irritable bowel syndrome (IBS) Trihexyphenidyl, benztropine • Parkinson disease #AntiMuscarinic #Agonists #Antagonists #Medications #Pharmacology #Table