Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Lymphadenitis #HSV #Pathology ... #Microscopy #Clinical ... #LymphNode
Eyelid Melanoma - Despite conservative interventions, the stye had persisted and the skin had become noticeably
Eyelid Melanoma ... lentigo maligna melanoma ... C) #Clinical #Pathology ... #Derm #Eyelid # ... Melanoma #Microscopy
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical ... #Microscopy
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... expression of Kell ... granulomatous disease ... Syndrome #Smear #Pathology ... #Microscopy #Clinical
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Graft versus Host disease ... notable satellite cell ... #versus #Host #disease ... #Pathology #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical ... #Microscopy
Focus of Metastatic Melanoma Colonizing a Germinal Center

I thought these big cells were funny immunoblasts- until
of Metastatic Melanoma ... thought these big cells ... of metastatic melanoma ... germinal #center #Pathology ... #Clinical #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Warthin-Finkeldey type giant cells ... Monocytoid B cells ... Lymphadenitis #PatternA #Pathology ... #Microscopy #LymphNode
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
Microscopic examination ... multinucleated giant cells ... #Clinical #Derm ... #Pathology #Herpes ... Tzsanck #Smear #Microscopy
Eosinophilic angiocentric fibrosis: IgG4-related disease of the upper aerodigestive tract. Distinctive concentric (onion-skin) perivascular fibrosis and
: IgG4-related disease ... 50 IgG4+ plasma cells ... angiocentric #fibrosis #Pathology ... #Clinical #Microscopy