Pathnologic @pathnologic
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SMARCB1-deficient sinonasal carcinoma: high grade tumors with varying proportions of basaloid and plasmacytoid/rhabdoid cells; CK+, SMARCB1
SMARCB1-deficient ... sinonasal carcinoma ... plasmacytoid/rhabdoid cells ... #Pathology #Microscopy ... #Clinical
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... #Carcinoma #Pathology ... #Clinical #Microscopy
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Spironolactone Bodies ... Red blood cells ... endoplasmic reticulum in cells ... #Pathology #Clinical ... #Gross #Microscopy
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
cells arranged ... around the tumor cells ... #Cancer #Pathology ... #Clinical #Gross ... #Microscopy
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
Variant of Medullary Carcinoma ... every oncocytic thyroid ... tumor is a Hurthle cell ... #Pathology #Microscopy ... #Clinical