Pathnologic @pathnologic
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Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... and Howell Jolly bodies ... #Pathology #Hematology ... #Smear #Clinical ... #Microscopy
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
core, most plasma cells ... immunoglobulin (Russell bodies ... #Myeloma #CD138 ... PlasmaCells #BoneMarrow #Clinical ... #Pathology #Hematology
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
/ Mallory Denk Bodies ... Pigments #Pathology #Hepatology ... #Clinical #Microscopy
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Spironolactone Bodies ... Red blood cells ... endoplasmic reticulum in cells ... #Pathology #Clinical ... #Gross #Microscopy
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
Sezary #Syndrome #Cells ... #Clinical #Pathology ... #Smear #Microscopy ... #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... non-specific red cell ... polychromatophilic cells ... hemolytic #anemia #Hematology ... Pathology #Smear #Microscopy
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
notable satellite cell ... disease #Pathology #Microscopy ... #Dermatology #Clinical
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
pt w pure red cell ... Pathology #Smear #Microscopy ... #Hematology #Clinical
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Head&neck, Lymph Nodes ... fibrosis (A) and well-formed ... seen within giant cells ... Pathology #LymphNode #Clinical ... #Microscopy
Neoplastic plasma cells with nucleoli (left image) and intranuclear Dutcher body (right image).

Dutcher bodies are round,
Neoplastic plasma cells ... Dutcher bodies are ... #DutcherBody #Bodies ... Intranuclear #Pathology #Clinical ... #Smear #Microscopy