Pathnologic @pathnologic
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Path Geek - All things #pathology
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Trichodysplasia spinulosa: follicles plugged w/ hyperkeratotic & parakeratotic debris, excessive inner root sheath differentiation towards keratinization.
cytoplasmic trichohyalin granules ... Trichodysplasia #spinulosa #Pathology ... #Microscopy #Dermatology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... leukemia #APL #APML #Pathology ... #Hematology #Clinical
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
#neutrophils #BoneMarrow ... #Smear #Hematology ... #Pathology #Clinical
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
#PlasmaCells #BoneMarrow ... #Clinical #Pathology ... #Hematology
Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s
like it has a granular ... Pemphigus #Vulgaris #Pathology ... #Microscopy #Dermatology