Algorithms in Medicine @MatthewHoMD
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Matthew Ho, MD PhD https://twitter.com/MatthewHoMD
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Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... Diagnosis Algorithm ... Deficiency #Anemia #Differential ... #Diagnosis #Algorithm ... #ferritin #hematology
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Upper GI Bleed - ... Management Algorithm ... Upper GI bleed ... UGIB #GIBleed #Differential ... Diagnosis #management #Algorithm
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... Features of hematologic ... #Diagnosis #Algorithm ... #hematology #WBC
Lower GI Bleed - Differential Diagnosis Algorithm

 • Structural: Diverticulosis, Hemorrhoids, Post-polypectomy, Polyps & malignancy, Anal
Lower GI Bleed - ... Differential Diagnosis ... Algorithm • ... #Lower #GI #Bleed ... #Diagnosis #Algorithm
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Elevated aPTT / PT - Differential ... Diagnosis Algorithm ... aPTT #PT #INR #Algorithm ... #Hematology #differential
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... and Treatment Algorithm ... Syndrome #HES #Hematology ... diagnosis #management #algorithm
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Thrombocytopenia #Differential ... #Diagnosis #Algorithm ... #hematology #platelets
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Thrombocytosis #Platelets #Differential ... #Diagnosis #Algorithm ... #hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Macrocytic #Anemia #differential ... #diagnosis #algorithm ... #hematology #workup
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Pancytopenia - Differential ... Diagnosis Algorithm ... #Pancytopenia #Differential ... #Diagnosis #Algorithm ... #hematology #workup