Algorithms in Medicine @MatthewHoMD
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Matthew Ho, MD PhD https://twitter.com/MatthewHoMD
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Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
to Thrombotic Microangiopathy ... hemosiderin, Hepatic function ... #Thrombotic #Microangiopathy
Pulmonary Function Testing (PFT) Interpretation Algorithm

Restrictive Lung Disease:
 • Chest wall or neuromuscular disorders
 • Interstitial
Pulmonary Function ... Lung Disease Obstructive ... #Pulmonary #Function
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Primary Thrombotic Microangiopathy ... Primary #Thrombotic #Microangiopathy
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Macroangiopathic, Microangiopathic
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG)

SAAG ≥ 1.1:
 • Cirrhosis
 • Portal
tamponade • IVC obstruction
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
GI losses (NG suction
Algorithm for Suspected SVC Syndrome

SVC syndrome suspected: Facial/arm/neck edema, distended neck/chest veins, facial plethora, dyspnea, cough,
head or neck with functional
Stoma Indications, Output and Complications

Stoma Types:
 • End ileostomy
 • Loop ileostomy
 • End colostomy
 •
digestion • Bowel obstruction