Algorithms in Medicine @MatthewHoMD
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Matthew Ho, MD PhD https://twitter.com/MatthewHoMD
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Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Upper GI Bleed - ... Management Algorithm ... Upper GI bleed ... #GI #Bleed #UGIB ... Diagnosis #management #Algorithm
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Differential Diagnosis Algorithm ... , GU bleed, Gyn ... bleed, Epistaxis ... Differential #Diagnosis #Algorithm ... #ferritin #hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... and Treatment Algorithm ... Syndrome #HES #Hematology ... diagnosis #management #algorithm
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Features of hematologic ... Differential #Diagnosis #Algorithm ... #hematology #WBC
Lower GI Bleed - Differential Diagnosis Algorithm

 • Structural: Diverticulosis, Hemorrhoids, Post-polypectomy, Polyps & malignancy, Anal
Lower GI Bleed - ... Differential Diagnosis Algorithm ... #Lower #GI #Bleed ... Differential #Diagnosis #Algorithm
Lower GI Bleed - Management Algorithm

Suspected lower GI bleeding (LGIB):
 • Hematochezia 
 • Melena +
Lower GI Bleed - ... Management Algorithm ... Unstable (Rule out upper ... GI bleed) vs Stable ... GIBleed #management #Algorithm
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... granular casts/RTE; blend ... Nephritis #AIN #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... → Refer to hematology ... • Nonmalignant hematologic ... Differential #Diagnosis #Algorithm ... #hematology
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Differential Diagnosis Algorithm ... aPTT #PT #INR #Algorithm ... #Hematology #differential
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #hematology #platelets