10 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... Bone/joint pain Psychiatric ... Symptoms: Disorientation ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... suicide Other Symptoms ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Deficiency (21-OHD ... degrees of 21-OHD ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... at > 17 years old ... 2 settings - Symptoms ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Insulin + KCI. 3) ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
Defiant Disorder (ODD ... if present in >3 ... settings - ODD ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
- Must have >3 ... symptoms present ... individual is >18 years old ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry