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differential algorithm acute urine renal diseases hyponatremia kidneyinjury management syndromes treatment workup acutekidneyinjury ain ana anca antibodies antibody antineutrophil antinuclear
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sensitive) • AKI ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts ... #diagnosis
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic sydnrome ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
require urgent nephrology ... cases are caused ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... • Hepatorenal syndromes ... Epithelial cell casts ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• Red cell casts ... • White cell casts ... infection • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... urine sediment Microscopic ... hematuria: - RBC casts ... → Diagnostic of ... #nephrology #renal
Urine Microscopy Instructions 1) Spin fresh urine sample (10-15mL) in a centrifuge for 3-5 minutes - Don't
Urine Microscopy ... one drop on a microscope ... under lower power (casts ... #Instructions #nephrology ... #diagnosis
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Haemolytic-uraemic syndrome ... Nephrotic syndrome ... glomerular #diseases #nephrology ... #pathology #comparison ... #table #diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... #Differential #Microscopy ... #Diagnosis #Nephrology
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Kidney Injury (AKI ... - Urinalysis/microscopy ... rhabdo/TLS) Causes ... #Nephrology #Diagnosis ... #Algorithm #Causes
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