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diagnosis differential hematology management oncology workup dermatology generalized mds nephrology pancytopenia pruritus secondary systemic acute aki cancer chronic cord cystic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... syndrome (MDS)
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... syndromes are a ... • Anemia • Aplastic ... syndromes with ... syndromes with
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #Syndrome #MDS
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Non-lmmune: • HELLP Syndrome
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
HLH syndrome 5. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... marrow failure syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Differential Diagnosis Algorithm ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Causes #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
HLH syndrome 5 ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... marrow failure syndrome
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
clinical context and signs ... Anti-GBM, Anti-ds-DNA ... Abdominal compartment syndrome ... • Cardio-renal syndrome ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #causes
Causes of Hemiplegia - Differential Diagnosis Algorithm Cerebral Hemisphere (Contralateral motor cortex) • Aphasia • Apraxia •
Causes of Hemiplegia ... Differential Diagnosis Algorithm ... Brown-Sequard Syndrome ... #Hemiplegia #Neurology ... #Causes
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