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diagnosis hematology algorithm management oncology mds nephrology workup acute aki cord cystic disorders gravis hypertension indications injury mcv morphologic myasthenia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... • Hypocellular myelodysplastic ... syndrome (MDS)
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #Syndrome #MDS
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... group of disorders caused ... skin that are caused ... • Anemia • Aplastic ... blood count with differential
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
of chronic kidney ... Hypothyroidism, Myelodysplastic ... syndrome - Dr ... morphologic #mcv #differential ... #diagnosis #causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... clinical context and signs ... Anti-GBM, Anti-ds-DNA ... #causes
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
hypertension and signs ... disturbance, or acute kidney ... renal bruit or signs ... Neurologic disorders ... #Differential #
Causes of Cystic Renal Mass - Differential Diagnosis Algorithm Benign - Anechoic on ultrasound, Well-demarcated on ultrasound/CT,
Causes of Cystic ... Renal Mass - Differential ... Hippel-Lindau Syndrome ... Carcinoma - No signs ... #Differential #
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
distribution in the 30s ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... • Symptoms and signs ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... affects the skin, neurologic ... musculoskeletal systems • Kidneys ... tract, and often causes
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