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diagnosis differential hematology iron management nutrition thrombocytosis celiac disease erythematosus fe gastroenterology gca giantcell gravis lupus mds myasthenia myelodysplasia myelodysplastic
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Elite athletes • Chronic ... Loss (without anaemia ... ) #Iron #Deficiency
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Inflammation • Cancer ... • Early Iron Deficiency ... #Causes #Hematology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... pylori, Celiac, Enteritis ... : Gl lesions / cancer ... Inflammation: IBD, Chronic ... #diagnosis #anemia
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Differential Diagnosis Algorithm ... Waldenstroms, Rheumatoid arthritis ... and other chronic ... #Fe #algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... : • Acute or Chronic ... effect following treatment ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... disease • Iron-deficiency ... anemia unresponsive ... to treatment ... without discernable cause
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... Malignancy: Metastatic cancer ... • Infections: Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Marrow Failure • Chronic ... or folic acid deficiency ... factor (GCSF) treatments ... • Copper deficiency
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
syndrome, rheumatoid arthritis ... distribution in the 30s ... test - Cogan sign ... - Peek sign ... inhibition - Chronic
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA ... GCA #Temporal #Signs
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