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diagnosis management differential clinical algorithm pharmacology endocrinology nephrology treatment pathophysiology causes physicalexam video hypocalcemia table hyperkalemia hypercalcemia cardiology comparison ophthalmology
Impact and Challenges With Vitamin D to Treat Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease
Calcitriol ... - Suppresses SHPT ... or better than calcitriol ... or better than calcitriol ... Cholecalciferol #Calcitriol
Hormonal Regulation of the Blood Calcium concentration #Calcium #Regulation #Parathyroid #Calcitonin #Calcitriol #PTH #Endocrinology #Pathophysiology #Hormones
Regulation of the Blood Calcium ... concentration #Calcium ... Parathyroid #Calcitonin #Calcitriol
Indications for Parathyroidectomy in Primary Hyperparathyroidism • All patients with symptomatic PHPT • Serum calcium 1
with symptomatic PHPT ... • Serum calcium ... nephrocalcinosis, 24h urine calcium ... #Indications #PHPT
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Calcium-containing ... Calcitriol improves ... Sensipar #Cinacalcet #Calcitriol
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 Hypomagnesemia (Serum level < 1.7 mg/dL) Neuromuscular manifestations • Tremor, tetany, seizures • Weakness
Abnormalities of calcium ... Decreased synthesis of calcitriol
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
PTH: • Elevated Calcitriol ... Bony Mets - Calcium
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Autosomal Dominant Calcium ... Excess Vitamin D/Calcitriol ... Other • Excess Calcium
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Lithium use • Calcium-sensing ... prostate (release of calcitriol
Calcium Homeostasis Serum Calcium - PTH - Vitamin D Regulation #Calcium #Homeostasis #Pathophysiology #Autoregulation #VitaminD #PTH #Endocrinology
Calcium Homeostasis ... Serum Calcium ... Regulation #Calcium
Vitamin D Metabolism Fat-soluble vitamin Sources: dermal synthesis and food (dairy products, fish) Active form: calcitriol (1,25-OH Vitamin D) Main
) Active form: calcitriol
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