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differential causes oncology thrombocytosis ckd erythematosus extravascular hemodialysis hemolysis index intravascular leukemia lupus lymphocytic management mds myelodysplasia myelodysplastic nephrology normocytic
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... effect following treatment ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g. cancer ... defects (e.g. sickle cell ... anemia, G6PD deficiency ... Production #Index #hematology ... #diagnosis #calculation
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Algorithm Decreased ... RA, SLE, PRV, Chronic ... Inflammation • Cancer ... • Early Iron Deficiency ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... • Infections: Chronic ... #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... • Sickle cell ... immune-complex hemolytic anemia ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... or folic acid deficiency ... • Copper deficiency ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... disease • Prolidase deficiency ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... • Cervical cancer
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
Patients with Chronic ... - differential diagnosis ... pruritus • Hematologic ... pruritus (Iron deficiency ... anemia, Polycythemia
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... algorithm 2018. ... median age at diagnosis ... disease tolerate anemia ... #algorithm #hematology
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