17 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... disorder of unknown ... maculopapular rash ... #AOSD #rheumatology ... #treatment
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Algorithm Spurious ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... inherited bleeding disorder ... bruising • Skin ... factor VIII) Treatment ... #Diagnosis #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... of hair, eyes, skin ... sclerosis (white "ash ... • Addison's disease ... #skin #dermatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... glucocorticoid treatment ... symptoms (eg, skin ... #diagnosis #hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
maculopapular skin ... Treatment - Mild ... : NSAIDS Treatment ... #AOSD #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... - Rash: multiple ... , breast CA - Hematologic ... Treatment: - Systemic