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management differential oncology dermatology causes syndrome leukemia workup anemia chronic classification cold comparison druginduced gca hemolytic hepatology lupus lymphocytic signs
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... glucocorticoid treatment ... (eg, skin or esophageal ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... ) CLL Symptoms: ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... inherited bleeding disorder ... bruising • Skin ... factor VIII) Treatment ... #Diagnosis #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Algorithm Infectious ... Myeloproliferative disorders ... • Sickle Cell ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Hepatomegaly • Skin ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
and duration of symptoms ... angioedema Other symptoms ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Monoclonal IgM Includes Disorders ... significance (MGUS), CLL ... hemolytic #anemia #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... Algorithm Hodgkin ... pattern of spread, B symptoms ... pathophysiology #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
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