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management differential dermatology syndrome lupus sle symptoms causes erythematosus vasculitis oncology pediatrics peds workup classification dermatomyositis disorders pruritus rash secondary
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Diagnostic Schema ... Still's disease ... Systemic histoplasmosis ... Hyperferritinemia #Algorithm ... #Hematology
Manifestations of IgG4-related disease by organ system. The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... thickening Signs ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
Cutaneous and Systemic ... Interstitial lung disease ... tract - Cardiac disease ... Dermatomyositis #Diagnosis ... #Rheumatology
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... disease, Pulmonary ... disease (~93-95% ... Autoantibodies #diagnosis ... #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... Differential Diaqnoses ... solid cancers • Systemic ... #diagnosis #management ... #treatment #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... Skin manifestations ... : • Systemic steroids ... #pharmacology #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... disorders • Celiac disease ... effect following treatment ... #Hematology
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