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differential rheumatology management thrombocytopenia druginduced systemic testing activation arthritis bruising cerebritis classification cns comparison dermatology disease hemolytic high hyperkalemia laboratory
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... versus DIL • ... • Immunologic Workup ... life-threatening • Treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... , SCLE-DIL (terbinafine ... Discontinuation of causal ... Erythematosus ( ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... autoantibodies that will cause ... #Erythematosus ... #rheumatology #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Autoimmune • ITP • SLE ... • TTP/HUS • DIC ... #Algorithm #Causes ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Glucocorticoids, IL ... #Algorithm #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... genotypes): SS, SC, SE ... #Algorithm #workup ... #hematology #testing
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... • Immunologic Workup ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Algorithm Pinpoint ... Autoimmune Vasculitis (lupus ... deficiency Work ... #Algorithm #Causes
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... (systemic lupus ... erythematosus) ... purpura - DIC ... peds #pediatrics #diagnosis
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