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diagnosis symptoms signs management differential pharmacology cardiology nephrology endocrinology algorithm syndrome causes treatment complications infectiousdiseases msk lifecycle ophthalmology cdc hematology
ACEi/ARBs in COVID-19: Beneficial, Bad, or Benign? Preclinical studies suggest ACEi/ARB use increases ACE2 expression, raising concern
ACEi/ARBs in COVID ... studies suggest ACEi ... use increases ACE2 ... However, ACEi/ARB ... #Coronavirus #Pathophysiology
NSAID vs ACEI/ARB effects on the Kidneys Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAID vs ACEI/ARB ... that NSAIDs and ACEI ... ACEI/ARB's are often ... Nephrology #Renal #Pathophysiology
Proposed Pathophysiology of COVID19 Lung Injury My thoughts on COVID19 Lung Injury, centered around 1) ACUTE thrombotic
Proposed Pathophysiology ... due to unopposed ACE ... due to unopposed ACE2 ... #LungInjury #Pathophysiology
Pathophysiology of ACE inhibitor-induced angioedema: Angioedema is a vascular reaction associated with tissue (subcutaneous, submucosal) edema
Pathophysiology ... of ACE inhibitor-induced ... substances in ACE ... the presence of ACE ... Kininogen #Bradykinin #ACE
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... differential #diagnosis #pathophysiology
Renin-Angiotensin-Aldosterone System (RAAS) The kidneys produce renin in response to low blood pressure or low plasma
angiotensin-converting enzyme (ACE ... #Pathophysiology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
anemia (MAHA) Pathophysiology ... ) • Initiate ACEi ... uncontrolled with ACEi
Gout: Pathogenesis and Clinical Findings - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders -
Medications (ASA, ACE ... Hyperuricemia #Pathophysiology
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
renal tubules - ACE-inhibitors ... Hyperuricemia #Pathophysiology
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